The goals of the PubMed Redesign 2009 are to make PubMed easier to use, simplify the interface, refresh the look, better organize the text on the screen, and promote scientific discovery. The redesign will be available in about 2 weeks.  To preview the new design click on New PubMed from PubMed’s home page.

Click to find more information.
Also note – to view a Webcast of the redesign  or click on PubMed Tutorials under More Resources in the new design.